Lower recovery of muscle protein lost during starvation in old rats despite a stimulation of protein synthesis
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Lower recovery of muscle protein lost during starvation in old rats despite a stimulation of protein synthesis.
Sarcopenia could result from the inability of an older individual to recover muscle lost during catabolic periods. To test this hypothesis, we compared the capacity of 5-day-refed 12- and 24-mo-old rats to recover muscle mass lost after 10 days without food. We measured gastrocnemius and liver protein synthesis with the flooding-dose method and also measured nitrogen balance, 3-methylhistidine ...
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AENDO October 40/4
Mosoni, L., T. Malmezat, M. C. Valluy, M. L. Houlier, D. Attaix, and P. Patureau Mirand. Lower recovery of muscle protein lost during starvation in old rats despite a stimulation of protein synthesis. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E608–E616, 1999.—Sarcopenia could result from the inability of an older individual to recover muscle lost during catabolic periods. To test this hypoth...
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Aging is characterized by a progressive loss of muscle mass. A decrease of muscle protein synthesis stimulation has been detected in the postprandial state and correlated to a decrease of muscle protein synthesis sensitivity to leucine in vitro. This study was undertaken to examine the effect of a leucine-supplemented meal on postprandial (PP) muscle protein synthesis during aging. Adult (8 mo ...
متن کاملThe Study of SAD1/UNC-84 Domain Protein 1 in Muscle of Diabetic Male Wistar Rats
Objective: The purpose of this study was to measure the changes of the SUN1 protein levels on soleus muscle in diabetic male wistar rats. Materials and Methods: Twenty male Wistar rats with 10 weeks old and weighing 200-250 grams were selected. After two weeks, the rats were divided into two groups (diabetic group and healthy group). After 12 hours fasting, diabetes was induced by intraperiton...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 1999
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.1999.277.4.e608